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TORONTO NATUROPATHIC MEDICAL TESTING CENTRE









HORMONE TESTING / ENDOCRINOLOGY
FROM GENOVA DIAGNOSTICS LAB

Adrenocortex Stress Profile examines 4 saliva samples over a 24-hour period for levels of cortisol and DHEA, imbalances of which are associated with ailments ranging from obesity and chronic fatigue to immune deficiency and increased risk of cardiovascular disease.

Bone Resorption Assessment is a simple, direct urinary assay of pyridinium crosslinks and deoxypyridinoline, useful in identifying current rate of bone loss, lytic bone disease, and efficacy of bone support therapies.

Comprehensive Melatonin Profile analyzes three saliva samples for the secretion pattern of this important hormone. Melatonin imbalance has been associated with Seasonal Affective Disorder, infertility, sleep disorders, and compromised immune function.

Comprehensive Thyroid Assessment is a comprehensive analysis of thyroid hormone secretion and metabolism, including central thyroid regulation and activity, peripheral thyroid function, and thyroid autoimmunity. This serum test allows the practitioner to pinpoint commonly occurring imbalances that underlie a broad spectrum of chronic illness.

Essential Estrogen, Urine evaluate how estrogen is being processed in the body. The tests yield clinical insight into many estrogen-dependent conditions and provide important tools for monitoring dietary, lifestyle and hormone therapies.

Female Hormone Profile (Rhythm Plus) analyzes eleven saliva samples over a 28-day period for the levels of ß-estradiol, progesterone, and testosterone, providing clues about menstrual irregularities, infertility, endometriosis, breast cancer, and osteoporosis. The comprehensive profile includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin.

Hormonal Health Assessment provides a focused overview of hormonal balance in both pre-menopausal and post-menopausal women, using a single serum sample to evaluate dynamics of sex steroid metabolism that can profoundly affect a woman's health throughout her lifetime.

Male Hormone Plus Profile analyzes four saliva samples over a 24-hour period for levels of testosterone. Elevated levels suggest androgen resistance, while decreased levels can result from such causes as hypogonadism, hepatic cirrhosis, lipid abnormalities and aging. The comprehensive profile includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how testosterone is influenced by cortisol, DHEA, and melatonin.

Menopause Profile examines three salivary samples over a 5-day period to determine levels of ß-estradiol, estriol, estrone, progesterone, and testosterone for women who are menopausal. The comprehensive profile includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how the sex hormones are affected by the influences of cortisol, DHEA, and melatonin.


FROM ZRT LABS


Hormones Available for Testing (Saliva Collection):

AM Cortisol (C) is recommended with situational stress and fatigue; indicator of adrenal imbalance.

AM/PM Cortisol is recommended with excess stress, morning and evening fatigue, difficulty sleeping etc.; indicator of adrenal dysfunction.

Adrenal Function Test (AFT) is the best comprehensive assessment of adrenal gland function; recommended with excessive stress, chronic fatigue, sleep disorders and allergies; indicator of immune function. Tests; DHEA's and four cortisols: morning, noon, evening and night.

DHEA-S is recommended with androgen deficiency or excess symptoms; indicator of stress level, mental performance and insulin resistance.

Estradiol (E2) is the most predominant of the estrogens. Testing is recommended with symptoms of estrogen deficiency or excess; best tested in concert with progesterone, as an imbalance of these two hormones is associated with major symptoms of menopause and disorders of the reproductive system).

Estriol (E3) it is recommended that Estriol levels be measured when supplementing with a compounded preparation of bioidentical estrogens containing Estriol (e.g. "Biest" preparations contain estriol and estradiol OR "Triest" preparations containing estriol, estradiol and estrone).

Estrone (E1) it is recommended that Estrone levels be measured when supplementing with a compounded preparation of bioidentical estrogens containing Estrone (e.g. "Triest" preparations contain estrone, estradiol and estriol).

Hormone Profile I (5 Tests) is a good basic assessment of overall steroid hormone balance or imbalance and association with specific symptoms; indicator of hypothyroidism, bone loss and insulin resistance. Five Tests: Estradiol (E2), Progesterone (Pg), Testosterone (T), DHEA's, and morning Cortisol (C).

Hormone Profile II + PM Cortisol (6 Tests) is the best value for money; most comprehensive evaluation of overall hormone balance or imbalance; indicator of thyroid and adrenal function; breast cancer profile. Six Tests: Hormone Profile I plus pm Cortisol (C4)

Hormone Profile III + AFT (8 Tests) tests provides the most complete and in-depth evaluation of hormone balance, imbalance and interrelationship of specific hormone levels as related to symptoms of menopause, andropause and adrenal function. Eight Tests: Estradiol (E2), Progesterone (Pg), Testosterone (T), DHEA's, and 'Diurnal Cortisol' (All four cortisols: morning (C1), noon (C2), evening (C3) and night (C4).

Progesterone (Pg) is recommended with symptoms of deficiency or excess; best tested in concert with estradiol as an imbalance of these two hormones is associated with major symptoms of menopause and disorders of the reproductive system.

Testosterone (T) is recommmended with deficiency or excess symptoms; indicator of low sex drive, hair loss / excess, muscle and bone status.


BloodSpot Test Products

Fasting Insulin - Fasting Insulin in blood spot for the detection of insulin resistance is collected in the morning after a 12 hour fast and before eating or drinking. The home test kit facilitates optimal collection time for a fasting sample. Process involves a finger prick with lancet, dripping of blood spots and drying on filter paper. Kit is self-contained with step-by-step instructions, filter paper, 2 lancets, antiseptic wipes, etc.

Fasting Insulin in blood spot is collected in the morning with our home test kit, after a 12 hour fast and before eating or drinking.

Follicle Stimulating Hormone - (FSH) Marker of Menopause or Andropause onset.

Free Thyroxine (fT4) - Thyroxine is the main thyroid hormone produced by the thyroid. A well- regulated process causes thyroxine to generate the much more potent thyroid hormone T3 (Triiodothyronine).

Free Triiodothyronine (fT3) measures the level of active thyroid hormone T3. This level must remain within optimal range to keep the body functioning properly and is crucial for maintaining physical and mental health.

Lutenizing Hormone (LH) - Marker of Menopause or Andropause onset.

Male Profile I (T, SHBG, PSA) is an overall assessment of male vitality, performance and prostate health; indicator of prostate enlargement or cancer risk.

Male Profile II (IGF-1, T, SHBG, PSA) is the best comprehensive assessment of overall male health, vitality, and prostate health; indicator of Adult Growth Hormone deficiency, rapid aging and increased prostate cancer risk.

Prostate Specific Antigen (PSA) - PSA a protein produced by the prostate gland is an important indicator of prostatic enlargement or increased risk of prostate cancer. High PSA levels are a warning sign of prostate health risks. A normal PSA reading is prerequisite to initiating testosterone therapy.

Sex Hormone Binding Globulin (SHBG) - SHBG (sex hormone binding globulin) measurement is used as a relative index of overall exposure to all forms of estrogens, as an indirect index of estrogen interaction with the liver and as an indicator of bioavailable testosterone. High levels indicate excess exposure to estrogens and lower bio-availability of testosterone to tissues, It is recommended that SHBG be tested along with testosterone in order to determine an imbalance between testosterone and estrogen. Such an imbalance is an important indicator of Andropause onset and / or premature aging in men.

Somatomedin C (IGF-1) - IGF-1 is important because it is a reliable indicator of human growth hormone. IGF-1 needs to be within the expected range for this reason: Low IGF-1 levels indicate Adult Growth Hormone Deficiency associated with rapid aging, decreased muscle and bone mass, slowing cognition, low libido and poor quality of life.

Testosterone (T) is recommended with deficiency or excess symptoms; indicator of low sex drive, hair loss, muscle mass and bone status. It is recommended that Testosterone and SHBG be tested together to determine imbalances of testosterone and estrogen; an important indicator of Andropause onset and/or premature aging in men.

Thyroid Comprehensive Profile is an in-depth comprehensive assessment of overall thyroid function checking TSH, freeT4, freeT3, and TPO antibodies (Hashimotos). More than 10 million Americans have been diagnosed with thyroid disease, and another 13 million people are estimated to have undiagnosed thyroid problems in the U.S. alone. Women are at greatest risk, developing thyroid problems seven times more often than men.

Thyroid hormones are transported in the blood "bound" to Thyroid Binding Globulin (TBG), which temporarily holds them inactive. This protein may be manipulated by many illnesses and medications. Therefore, measurement of the "unbound," free levels of T3 and T4 thyroid hormones provides a more accurate interpretation. When TSH, free T3 and T4 are found to be within normal range, a functional thyroid deficiency may be suspected. This can be clarified by testing TPO antibodies (Thyroid Peroxidase Antibody) as part of the comprehensive thyroid panel.

Thyroid Peroxidase Antibody (TPO) - In 90% of patients with Hashimoto’s (autoimmune thyroiditis) TPO levels are elevated; indicator of other autoimmune disorders and polycystic ovaries.

Thyroid Stimulating Hormone (TSH) measures the amount of thyroid hormone manufactured by the thyroid gland. General indication of thyroid activity.

For more information on any of the tests listed above,
please call 416 913 4325 (HEAL).



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